Wave reflection and central pressure augmentation

Aortic pulse wave velocity, reflection site distance, and augmentation index.

Augmentation index, left ventricular contractility, and wave reflection.

Augmentation index (AIx), a correlate of mortality, is thought to be influenced by left ventricular contractility and wave reflections. However, the relationship of AIx with left ventricular contractility changes has never been assessed, and the wave reflection theory has recently been questioned. This study sought to examine arterial waveform changes in response to reduced "wave reflection" an...

Peripheral augmentation index and wave reflection in the radial artery.

Peripheral Augmentation Index and Wave Reflection in the Radial Artery To the Editor: We were interested to read the recent article by Munir et al1 and congratulate them on making a valuable contribution to the field of pulse wave analysis. They and Payne and Webb, in their accompanying editorial,2 ponder why the late systolic shoulder (SBP2) corresponds so closely with central systolic blood p...

The 24-hour pulse wave velocity, aortic augmentation index, and central blood pressure in normotensive volunteers

The purpose of this study was to examine the pulse wave velocity, aortic augmentation index corrected for heart rate 75 (AIx@75), and central systolic and diastolic blood pressure during 24-hour monitoring in normotensive volunteers. Overall, 467 subjects (206 men and 261 women) were recruited in this study. Participants were excluded from the study if they were less than 19 years of age, had b...

Cyclooxygenase inhibition augments central blood pressure and aortic wave reflection in aging humans.

The augmentation index and central blood pressure increase with normal aging. Recently, cyclooxygenase (COX) inhibitors, commonly used for the treatment of pain, have been associated with transient increases in the risk of cardiovascular events. We examined the effects of the COX inhibitor indomethacin (Indo) on central arterial hemodynamics and wave reflection characteristics in young and old ...